サイテーション
-
Rationally designed light-inducible RNA-releasing protein for translational regulation and optogenetic control of gene therapies
Author:
Shichao Li, Ting Gao, Yinhao Wang, Zhizhi Wang, Jiawei Shao, Mingqi Xie
Journal: Trends in Biotechnology
Doi: https://www.doi.org/10.1016/j.tibtech.2026.03.004
2026/4/8 -
The exonic SNP rs11676272-C risk allele mediates diet-induced obesity and reduces enhancer activation
Author:
Weina Wang, Yue Li, Sheng Dong, Yuwei Liu, Chenghang Guo, Yuzhe Su, Wei Tian, Xiaoyu Hu, Zhenshan Wang
Journal: EMBO REPORTS
Doi: https://www.doi.org/10.1038/s44319-026-00758-9
2026/4/6 -
Telomere recapping prevents pathogenic telomere-to-mitochondrial DNA communication in heart failure
Author:
Yinlong Zhao , Xiaolu Bao , Weiyao Xiong , Xin Wan , Qingying Yu , Teng Wang , Andrew C H Chang , Alian Zhang , Peng Zhang , Zhenhao Lin , Han Gao , Yangyang Liu , Yanqiu Wang , Ching Shang , Euan A Ashley , Ming Lei , Jianyi Zhang , Junfeng Zhang , Wei Han , Alex C Y Chang
Journal: Cardiovascular Research
Doi: https://www.doi.org/10.1093/cvr/cvag077
2026/4/6 -
Engineered hematopoietic stem cells give rise to therapeutic antibody secreting B cells
Author:
Matthew Porteus, Sofia Luna, William Feist, Ashley Utz, Jumana Afaghani, Masashi Miyauchi, Hana Ghanim, Freja Ekman, Anais Amaya, Sridhar Selvaraj, Norman Russkamp, Ludwig Schmiderer
Journal: Research Square
Doi: https://www.doi.org/10.21203/rs.3.rs-9269825/v1
2026/4/5 -
Aging-dependent microglial heterogeneity worsens outcomes in models of traumatic brain injury
Author:
Zhichao Lu, Yi Shuai, Chenxing Wang, Zongheng Liu, Ziheng Wang, Qianqian Liu, Rui Jiang, Jue Zhu, Yongqi Zhu, Weiquan Liao, Xingjia Zhu, Jingwei Zhao, Kaibin Shi, Wei Shi, and Peipei Gong
Journal: The Journal of Clinical Investigation
Doi: https://www.doi.org/10.1172/JCI196112
2026/4/2 -
Endogenous Sox2 expression is essential for Atoh1-induced hair cell addition and regeneration in the mouse utricle
Author:
Yu-Tong Yang, Jing-Ying Guo, Jun-Yi Xu, Wei- Su, Ming-Yu Hao, Ting Zhang, Shu-Sheng Gong, Guo-Peng Wang
Journal: Neuroscience
Doi: https://www.doi.org/10.1016/j.neuroscience.2026.03.051
2026/3/31 -
Human promoter-driven AAV tools enable precision gene therapy targeting cochlear hair cells
Author:
Liyan Zhang, Yicheng Lu, Xianmin Wu, Jinyi Fan, Xinru Zhang, Yang Xu, Hao Wei, Qiuhan Sun, Lulu Jiang, Huawei Tuo, Nianci Li, Hua Jin, Wu Cao, Beibei Ye, Ziyu Zhang, Yunkai Zhang, Fangyi Chen, Ling Lu, Jieyu Qi, Renjie Chai, Fangzhi Tan
Journal: Cell Reports Medicine
Doi: https://www.doi.org/10.1016/j.xcrm.2026.102725
2026/3/31 -
Olfactory epithelium organoid models identify Ddit3 as a potential therapeutic target against inflammation-related olfactory sensory neuronal loss and functional deficit
Author:
Jinxia Liu, Jiaming Qi, Nan Jiang, Yuzhen Wang, Weihao Li, Shiyi Tian, Liujing Zhuang, Yunfeng Zhang, Yongliang Liu, Yiqun Yu
Journal: International Journal of Biological Sciences
Doi: https://www.doi.org/10.7150/ijbs.129192
2026/3/30 -
Modulation of PKCα/ETS1 by klotho restores CYB5R4-dependent mitochondrial function in proximal tubular epithelial cells to attenuate the progression of diabetic kidney disease
Author:
Chun Gan, Xindi Zhou, Lan Qiu, Dan Chen, Yulu Shi, Qing Yang, Huimin Jiang, Han Xiao, Wanbing Chen, Xuejun Yang, Yaxi Chen, Mo Wang, Haiping Yang, Wei Jiang, Qiu Li
Journal: Cardiovascular Diabetology
Doi: https://www.doi.org/10.1186/s12933-026-03150-y
2026/3/28 -
Identification Of a Therapeutic Threshold For AAV-STXBP1 Gene Therapy in a Rodent Model of STXBP1 Developmental & Epileptic Encephalopathy
Author:
Nicholas B. Gallo, John W. Annand, Pete Clarner, Brian Harvey, Elena Morozova, Christian Ehrenfels, Ting Jiang, Long Yuan, Samneet Kashyap, Xiaodong Lu, Jinkuk Choi, Jennifer Zoll, Anh Nhu, Ashton Brennecke, Purvish Patel, Davide Gianni, Edward Guilmette, Sarah Geisler, Adam Sheehy, Kevin Ghaemi, Sam Benezra, Ayan Ghoshal, Yuqing Liu, Thomas Carlile, Shaolong Cao, Fergal Casey, Samir Koirala, Sijia Wu
Journal: Molecular Therapy
Doi: https://www.doi.org/10.1016/j.ymthe.2026.03.027
2026/3/24 -
Template-independent genome editing and restoration for correcting frameshift disorders
Author:
Shiwei Qiu, Lian Liu, Bin Xiang, Ziqin Jin, Yahong Li, Dong Li, Hanqing Hou, Kuan Li, Gege Wei, Jiangping Xie, Shang Li, Shuang Liu, Chunlai Chen, Xin Liang, Qianwen Sun & Wei Xiong
Journal: Nature Biomedical Engineering
Doi: https://www.doi.org/10.1038/s41551-026-01635-5
2026/3/23 -
Functional Evaluation of Computationally Designed IL-10 in IL-10 KO Mice
Author:
Jordan Stokes 1,Iram Hyder 1,Zhihang Shen 2ORCID,Peter Ramdhan 2ORCID,Allison Bayer 3,Clive Wasserfall 3,Chenglong Li 2,* andSihong Song 1,*
Journal: Biomolecules
Doi: https://www.doi.org/10.3390/biom16030482
2026/3/23