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Base editing as a genetic treatment for spinal muscular atrophy
Author:
Christiano R. R. Alves, Leillani L. Ha, Rebecca Yaworski, Cicera R. Lazzarotto, Kathleen A. Christie, Aoife Reilly, Ariane Beauvais, Roman M. Doll, Demitri de la Cruz, Casey A. Maguire, Kathryn J. Swoboda, Shengdar Q. Tsai, Rashmi Kothary, and Benjamin P. Kleinstiver
Journal: BioRxiv
Doi: https://www.doi.org/10.1101/2023.01.20.524978
Jan 21 2023 -
2D Catalytic, Chemodynamic, and Ferroptotic Vermiculite Nanomedicine
Author:
Lifang Ma, Hui Huang, Wei Feng, Liang Chen, Lili Xia, Yongchun Yu, Jiayi Wang, Yu Chen
Journal: Advanced Functional Materials
Doi: https://www.doi.org/10.1002/adfm.202208220
Oct 11 2022 -
Rational design of AAVrh10-vectored ACE2 functional domain to broadly block the cell entry of SARS-CoV-2 variants
Author:
Minchao Li, Jiaoshan Chen, Yajie Liu, Jin Zhao, Yanjun Li, Yunqi Hu, Yao-qing Chen, Litao Sun, Yuelong Shu, Fengling Feng, and Caijun Sun
Journal: Antiviral Research
Doi: https://www.doi.org/10.1016/j.antiviral.2022.105383
Jul 30 2022 -
Circular single-stranded DNA is a superior homology-directed repair donor template for efficient genome engineering
Author:
Keqiang Xie, Jakob Starzyk, Ishita Majumdar, Katerina Rincones, Thao Tran, Danna Lee, Sarah Niemi, John Famiglietti, Bernhard Suter, Richard Shan and Hao Wu
Journal: BioRxiv
Doi: https://www.doi.org/10.1101/2022.12.01.518578
Dec 2 2022 -
TRIM28 regulates SARS-CoV-2 cell entry by targeting ACE2
Author:
Yinfang Wang, Yingzhe Fan, Yitong Huang,Tao Du, Zongjun Liu, Dekui Huang, Ying Wang, Nanping Wang, and Peng Zhang
Journal: Cell Signal
Doi: https://www.doi.org/10.1016/j.cellsig.2021.110064
Jun 17 2021 -
Emergence of SARS-CoV-2 spike RBD mutants that enhance viral infectivity through increased human ACE2 receptor binding affinity
Author:
Junxian Ou, Zhonghua Zhou, Ruixue Dai, Shan Zhao, Xiaowei Wu, Jing Zhang, Wendong Lan, Lilian Cui, Jianguo Wu, Donald Seto, James Chodosh, Gong Zhang, and Qiwei Zhang
Journal: BioRxiv
Doi: https://www.doi.org/10.1101/2020.03.15.991844
Sep 12 2020 -
Intravenous injection of AAV-PHP.eB across the blood-brain barrier in the adult mouse for central nervous system gene therapy
Author:
Yongwei Shu, Jie Yao, Yang Qu, Jing Zheng, Jing Ding, Lina Zhang, Yefan Wang, Linlin Zhao, Jingyu Zhang, Siqi Tang
Journal: Oncology and Translational Medicine
Doi: https://www.doi.org/10.1007/s10330-018-0313-3
Feb 2019 -
Mini-dCas13X–mediated RNA editing restores dystrophin expression in a humanized mouse model of Duchenne muscular dystrophy
Author:
Guoling Li, Ming Jin, Zhifang Li, Qingquan Xiao, Jiajia Lin, Dong Yang, Yuanhua Liu, Xing Wang, Long Xie, Wenqin Ying, Haoqiang Wang, Erwei Zuo, Linyu Shi, Ning Wang, Wanjin Chen, Chunlong Xu, and Hui Yang
Journal: J Clin Invest
Doi: https://www.doi.org/10.1172/JCI162809
Feb 1 2023 -
NeuroD1 Regulated Endothelial Gene Expression to Modulate Transduction of AAV-PHP.eB and Recovery Progress after Ischemic Stroke
Author:
Xiaosong He, Xin Wang, Hui Wang, Tao Wang, Fuhan Yang, Yuchen Chen, Zifei Pei, Yuting Bai, Wen Li, Zheng Wu, Gong Chen
Journal: Aging and Disease
Dec 20 2023 -
METTL5-mediated 18S rRNA m6A modification promotes corticospinal tract sprouting after unilateral traumatic brain injury
Author:
Zhenpeng Li, An Jiang, Jintao Fang, Yifei Jiang, Wenting He, Liwei Yan, Shuai Qiu, Bengang Qin, Qingtang Zhu, Honggang Wang
Journal: Experimental Neurology
Oct 13 2024 -
Somatic BrafV600E mutation in the cerebral endothelium induces brain arteriovenous malformations
Author:
Tianqi Tu, Chendan Jiang, Jingwei Li, Shiju Zhang, Ziwei Cui, Xiaosheng Meng, Dong Xing, Hongqi Zhang & Tao Hong
Journal: Angiogenesis
May 3 2024 -
Rational design of a Lfng-enhancer AAV construct drives specific and efficient gene expression in inner ear supporting cells
Author:
Richard Seist, Juwan S. Copeland, Litao Tao, Andrew K. Groves
Journal: Hearing Research
Mar 2025