サイテーション
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METTL3-mediated m6A Methylation Modification Promotes the Endothelial Cell Pyroptosis in Kawasaki Disease
Author:
Bingbing Qiu, Chengyi Wang, Changdi Chen, Xuemin Zhu & Guanghua Liu
Journal: Applied Biochemistry and Biotechnology
Doi: https://www.doi.org/10.1007/s12010-025-05441-8
2025/11/3 -
Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins
Author:
Wenjian Han, Bo Yuan, Xiaojuan Fan, Weike Li, Yiting Yuan, Yuefang Zhang, Shu Wang, Shifang Shan, Markus Hafner, Zefeng Wang, Zilong Qiu
Journal: Nat Commun
Doi: https://www.doi.org/10.1038/s41467-025-64748-6
2025/11/4 -
Multiplex neurodegeneration proteotoxicity platform reveals DNAJB6 promotes non-toxic FUS condensate gelation and inhibits neurotoxicity
Author:
Samuel J Resnick, Seema Qamar, Pushya Krishna, Vladislav Korobeynikov, Hannes Ausserwoger, Alyssa Miller, Pietro Esposito, Juan A Varela, Jenny Sheng, Lei Haley Huang, Jonathon Nixon-Abell, Schuyler Melore, Chyi Wei Chung, Nino F Läubli, Sofia Kapsiani, Xuecong Li, Jingshu Wang, Nancy Zhang, Mahabub Maraj Alam, Alondra S Burguete, Theresa C Swayne, Yanyan Chen, Ya-Cheng Liao, Neil A Shneider, Michele Vendruscolo, Tuomas P J Knowles, Clemens F Kaminski, Francesco Simone Ruggeri, Gabriele S Kaminski Schierle, Peter St George-Hyslop, Alejandro Chavez
Journal: Nat Commun
Doi: https://www.doi.org/10.1038/s41467-025-65178-0
2025/11/21 -
Tianma-Chuanxiong synergically inhibit glioma by regulating the miR-101/COX-2/AKT signal
Author:
Zhou Xin-yi, Xu Chun-qi, Lai Nian-hong, Hu Ying, Zhang En-xin, Wu Wen-jiang, Zeng Jia-xin, Liu Bo, Zhang Xiao-jun
Journal: Journal of Ethnopharmacology
Doi: https://www.doi.org/10.1016/j.jep.2025.120939
2025/11/20 -
A Novel miniALPK3 Gene Therapy for ALPK3-Associated Cardiomyopathy
Author:
Wei Feng, Julijus Bogomolovas, Abraham Grant Shain, Li Wang, Chao Chen, Mao Ye, Yusu Gu, Xiaohai Zhou, Ju Chen
Journal: Circulation
Doi: https://www.doi.org/10.1161/CIRCULATIONAHA.125.074632
2025/11/19 -
Long-Term Attenuation of Vascular Hyperpermeability in a Hereditary Angioedema Mouse Model by Adenine Base Editing
Author:
Yang Wang, Yuxuan Kong, Yingjie Zhang, Yunjie He, Wei Wang, Yuanbin Lu, Juan Meng, Huijun Yuan
Journal: Allergy
Doi: https://www.doi.org/10.1111/all.70152
2025/11/14 -
Skeletal muscle-derived IL-33 mediates muscle-to-bone crosstalk and regulates bone metabolism via CD8+ T cell-secreted CCL5
Author:
Mingchong Liu, Yi Han, Jiaming Wang, Yimin Zhu, Yueqi Zhang, Qining Chu, Chensong Yang, Bingdi Chen, Guixin Sun
Journal: eBioMedicine
Doi: https://www.doi.org/10.1016/j.ebiom.2025.106024
2025/11/13 -
Reversible synaptic deficits in early-stage Batten disease
Author:
Masood Ahmad Wani, Chloe M. Hall, Thomas Mittmann, Benedikt Grünewald, Jakob von Engelhardt
Journal: BioRxiv
Doi: https://www.doi.org/10.1101/2025.11.12.687979
2025/11/12 -
The role of GPD2 on ferroptosis in sepsis-induced acute lung injury
Author:
Ying Han, Chunfang Dai, DanDan Hu, Yu Yao, Wanwan Peng, Yijun Zheng, Qiyi Zeng, Hairui Xie, Jinda Huang
Journal: Biochemical and Biophysical Research Communications
Doi: https://www.doi.org/10.1016/j.bbrc.2025.153066
2026/1/1 -
Activating PPARα in macrophages attenuates arterial remodeling via inhibiting YAP nuclear localization
Author:
Xinxin Lin, Xiaocong Liu, Jinglin shi, Tuohong Sun, Ting Feng, Benrui Sun, Hongbin Liang, Qiuxia Zhang, Guojun Chen, Siyu Chen, Alex Pui-Wai Lee, Shenjian Luo, Jiancheng Xiu, Xinlu Zhang
Journal: Biochemical Pharmacology
Doi: https://www.doi.org/10.1016/j.bcp.2025.117566
2025/11/28 -
Base editing strategies for in vivo correction of two highly recurrent phenylketonuria variants
Author:
Aidan Quigley, Ishaan Jindal, Thomas Campion, Delaney Rutherford, Yongseok Han, Walsh Quigley, Ping Qu, Kiran Musunuru, Rebecca Ahrens-Nicklas, Xinying Hong, Xiao Wang
Journal: Molecular Therapy
Doi: https://www.doi.org/10.1016/j.omtn.2025.102770
2025/12/9 -
A novel gene delivery platform based on a commensal human anellovirus demonstrates transduction in multiple tissue types
Author:
Cato Prince, George Bounoutas, Bolu Zhou, Waseem Raja, Isabella Gold, Riana Pozsgai, Parmi Thakker, Nicole Boisvert, Christopher Reardon, Stephanie Thurmond, Erin Ozturk, Rajendra Boggavarapu, Jenna Antonucci Johnson, Patricio Jeraldo, Simeon Springer, Lovepreet Chahal, Emily Stead, Cameron Dodier, Bryan Vought, Maciej Nogalski, Dhananjay Nawandar, Christopher Wright, Ashley Mackey, Geoffrey Parsons, Joseph Cabral
Journal: Molecular Therapy
Doi: https://www.doi.org/10.1016/j.omtm.2025.101597
2025/12/11